Centrespace Gallery is located in Leonard Lane, just off Corn Street, Bristol's main central café/bar area.

Leonard Lane is one of the ancient lanes of Bristol that run along the old city boundary near the 15th century city gates. You can approach Leonard Lane from the entrance on Corn Street, the steps on St. Stephens Street or the entrance on Small Street.

Within 300 meters of Centrespace Gallery are The Arnolfini, The Watershed media centre and the main shopping areas of Bristol. There is a limited amount of meter parking available in Corn Street and most of the major bus routes arrive and depart through Colston Street and St Augustines parade less than 200 meters away. There is additional parking at the Galleries Shopping Centre near by. The Gallery has enabled access for people with a disability and there is ample provision for securing cycles in the lane.